Why the study?
Does continuous infusion of urokinase through an intracoronary perfusion wire improve thrombus resolution and patency in patients with visible intracoronary thrombus undergoing PTCA?
Population
33 patients with visible intracoronary thrombus in native vessels or saphenous vein grafts prior to or…
Design
Case_series
Follow-up
24 hours
Authors
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May support urokinase perfusion wire use in thrombotic PTCA; hypothesis-generating and requires randomized confirmation.
Does continuous infusion of urokinase through an intracoronary perfusion wire improve thrombus resolution and patency in patients with visible intracoronary thrombus undergoing PTCA?
Continuous intracoronary infusion of urokinase via a perfusion wire for 24 hours is a safe and effective technique for resolving visible thrombus and facilitating successful PTCA.
Chapekis et al. (1991) studied this question.
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