Why the study?
Does prolonged intracoronary infusion of urokinase followed by balloon angioplasty cause hemorrhagic myocardial infarction in a patient with an occluded saphenous vein bypass graft?
Does prolonged intracoronary infusion of urokinase followed by balloon angioplasty cause hemorrhagic myocardial infarction in a patient with an occluded saphenous vein bypass graft?
Prolonged intracoronary infusion of urokinase followed by balloon angioplasty in an occluded saphenous vein graft can lead to hemorrhagic myocardial infarction.
May signal hemorrhagic MI risk after prolonged urokinase before angioplasty in occluded SVGs; leaves open causality and generalizability.
A 0.038 inch perfusion wire was used to selectively administer a 24‐hr infusion of urokinase into the occluded saphenous vein bypass graft of a 69‐yr‐old woman. Immediately following subsequent reperfusion by balloon angioplasty, she developed a hemorrhagic myocardial infarction.
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Bedotto et al. (1992) studied this question.
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