Why the study?
Does combined intracoronary and intravenous urokinase infusion resolve thrombus-containing saphenous vein graft stenoses?
Does combined intracoronary and intravenous urokinase infusion resolve thrombus-containing saphenous vein graft stenoses?
Combined intracoronary and intravenous urokinase infusion may be an effective alternative to angioplasty for resolving thrombus-containing saphenous vein graft stenoses.
May support urokinase for thrombus-laden SVG stenoses; hypothesis-generating and requires prospective validation.
A subtotally occlusive saphenous vein graft stenosis resolved after rapid intracoronary and prolonged intravenous urokinase infusion. Additional therapy was unnecessary, avoiding the attendant risks of saphenous vein graft angioplasty. Combined intracoronary and intravenous urokinase infusion should be considered prior to coronary angioplasty of saphenous vein graft stenoses, particularly when diffuse degeneration is present or the risk of underlying thrombus is high.
No takes yet. Share an insight, caveat, or question.
Cospito et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: