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March 1, 1996Journal of Cardiovascular Electrophysiology

Management of Ventricular Fibrillation with Transvenous Defibrillators Without Baseline Electrophysiologic Testing or Antiarrhythmic Drugs

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Why the study?

Does management with transvenous ICDs without baseline EPS or antiarrhythmic drugs result in successful outcomes in survivors of out-of-hospital VF?

Population

66 survivors of an initial episode of out-of-hospital VF not associated with a Q wave myocardial infarction…

Design

Cohort

Follow-up

average 25 +/- 12 months

Authors

GDG. Lee DolackJPJeanne E. PoolePKPeter J. Kudenchuk

Discussion

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Overview

Supports ICD-only management without baseline EPS or AADs in out-of-hospital VF survivors; hypothesis-generating and requires randomized confirmation.

Structured PICO

Does management with transvenous ICDs without baseline EPS or antiarrhythmic drugs result in successful outcomes in survivors of out-of-hospital VF?

P
Population
66 survivors of an initial episode of out-of-hospital VF not associated with a Q wave myocardial infarction or reversible causes, average age 58 +/- 11 years, 79% male. Excluded: previous history of monomorphic VT, clinical history suggestive of SVT, or preoperative EP testing.
I
Intervention
Transvenous multiprogrammable implantable cardioverter defibrillators (ICDs) as first-line therapy without baseline electrophysiologic study (EPS) or antiarrhythmic drugs
O
Outcome
Survival free of death from any causehard clinical

Survivors of primary out-of-hospital VF can be successfully managed with transvenous ICDs without the need for baseline electrophysiologic testing or chronic antiarrhythmic drug therapy.

Cite This Study

Dolack et al. (1996) studied this question.

synapsesocial.com/papers/6a76fb7f137c7dcc81bd8729https://doi.org/10.1111/j.1540-8167.1996.tb00515.x
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