Why the study?
Does cold stimulation of peripheral thermoreceptors affect fetal heart rate and variability in fetal sheep?
Population
Chronically catheterized fetal sheep aged 140-144 days
Comparison
Injection of 25 mL ice-cold saline over the… vs Baseline measurements before cold saline…
Design
Preclinical
Follow-up
100 seconds
Authors
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May influence fetal HRV via sympathetic pathways in sheep; hypothesis-generating and should not yet inform clinical practice.
Does cold stimulation of peripheral thermoreceptors affect fetal heart rate and variability in fetal sheep?
Cold stimulation of peripheral thermoreceptors in fetal sheep increases heart rate and variability via the sympathetic nervous system, without vagal involvement.
Yu et al. (2000) studied this question.
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