An isolated lesion at the obex in a patient with multiple sclerosis was correlated with recurrent episodes of noncardiogenic pulmonary edema.
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Obex lesion correlation with recurrent noncardiogenic edema in MS warrants clinical vigilance for brainstem involvement; leaves open causality and generalizability.
A 27-year-old woman with a recent diagnosis of multiple sclerosis developed several episodes of noncardiogenic pulmonary edema over a 3-month period, each requiring intubation and ventilatory support. The development and subsequent resolution of an isolated lesion at the obex was correlated with the episodes. The literature regarding the anatomical basis of neurogenic pulmonary edema is reviewed.
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Simon et al. (1991) studied this question.
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