Key result
A vaccine-derived, human-bovine double reassortant G1P[8] rotavirus was detected in a 7-year-old schoolgirl with acute gastroenteritis who had no known contact with recently vaccinated infants.
Case Report (n=1)
Highlights the potential for vaccine-derived rotavirus to remain stable in the environment and cause gastroenteritis in individuals without direct contact with vaccinated infants.
Consider vaccine-derived rotavirus in unexplained gastroenteritis without exposure; case report leaves open environmental transmission risk.
We describe a case of acute gastroenteritis in a schoolgirl associated with a detection of vaccine-derived, human-bovine double reassortant G1P[8] rotavirus, without any known contact with recently vaccinated infants. We propose that human-bovine double reassortant G1P[8] may be formed in RotaTeq-vaccinated infants and can occasionally cause gastroenteritis symptoms in vaccine recipients who may rarely transmit the virus to close contacts. The present case suggests that such viruses can remain stable in environment longer than 1 transmission cycle.
No takes yet. Share an insight, caveat, or question.
Hemming et al. (2013) conducted a case report in Acute gastroenteritis (n=1). Vaccine-derived, human-bovine double reassortant G1P[8] rotavirus was evaluated on Detection of vaccine-derived rotavirus and gastroenteritis symptoms. A vaccine-derived, human-bovine double reassortant G1P[8] rotavirus was detected in a 7-year-old schoolgirl with acute gastroenteritis who had no known contact with recently vaccinated infants.