Key result
During a course of electroconvulsive therapy, the time for heart rate to return halfway to baseline (Time 1/2) gradually shortened and was positively correlated with EEG seizure duration.
Why the study?
Does the course of electroconvulsive therapy alter cardiac autonomic nervous system activity in patients with major depressive disorder?
Population
12 patients with major depressive disorder
Design
Cohort
Follow-up
throughout the course of electroconvulsive therapy
Authors
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Shorter heart rate recovery time over ECT sessions correlates with seizure duration; leaves open whether autonomic adaptation influences treatment response or safety in depression.
Observational (n=12)
Does the course of electroconvulsive therapy alter cardiac autonomic nervous system activity in patients with major depressive disorder?
The duration of sympathetic nervous system activation induced by electroconvulsive therapy gradually shortens over the course of treatment and correlates with EEG seizure duration.
Suzuki et al. (2018) conducted an observational in Major depressive disorder (n=12). Electroconvulsive therapy was evaluated on Changes in heart rate (Time 1/2 and Time Max) and relationship with EEG seizure duration. During a course of electroconvulsive therapy, the time for heart rate to return halfway to baseline (Time 1/2) gradually shortened and was positively correlated with EEG seizure duration.
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