Key result
In a 37-year-old woman with typical chest pain and mild high-sensitivity troponin elevation, 82Rb PET/CT and coronary angiography revealed severe proximal LAD stenosis requiring stenting.
Why the study?
Minor high-sensitivity troponin elevations are often attributed to noncardiac etiologies, though any elevation remains concerning in patients presenting with characteristic symptoms.
Case Report (n=1)
Minor high-sensitivity troponin elevations in young patients with typical chest pain warrant high clinical suspicion and timely imaging for obstructive coronary artery disease.
Minor hs-troponin elevations with typical pain may signal obstructive CAD in young patients; this case leaves open need for prospective validation.
In the era of high-sensitivity troponin, minor elevations are often attributed to noncardiac etiologies. However, in patients who present with characteristic symptoms, any troponin elevation is concerning. We detail a case of a 37-y-old woman who presented to an outside hospital with typical chest pain and had a mild elevation in high-sensitivity troponin. Given her overall stability, she was discharged with outpatient cardiology follow-up. ⁸²Rb PET/CT myocardial perfusion imaging test demonstrated a large, reversible anteroseptal perfusion defect. Coronary angiography revealed severe (80%) stenosis in the proximal left anterior descending artery treated with a single stent. This case highlights the need to have a high index of suspicion in young people with minor troponin elevations and pursue timely imaging.
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Annabathula et al. (2025) conducted a case report in Typical chest pain with mild high-sensitivity troponin elevation (n=1). 82Rb PET/CT myocardial perfusion imaging and coronary angiography was evaluated on Diagnosis of coronary artery disease. In a 37-year-old woman with typical chest pain and mild high-sensitivity troponin elevation, 82Rb PET/CT and coronary angiography revealed severe proximal LAD stenosis requiring stenting.
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