Key result
In a 32-year-old woman with peripartum cardiomyopathy, surgical thrombectomy followed by aggressive anticoagulation with intravenous heparin and warfarin successfully resolved recurrent left ventricular apical thrombi without embolism.
Case Report (n=1)
Aggressive and pre-emptive anticoagulation with heparin and warfarin may be necessary in peripartum cardiomyopathy to prevent and treat recurrent left ventricular thrombus, even in patients with normal sinus rhythm.
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May support aggressive anticoagulation for recurrent LV thrombi in peripartum cardiomyopathy; leaves open need for prospective validation before practice change.
Shimamoto et al. (2008) conducted a case report in Peripartum cardiomyopathy with recurrent left ventricular apical thrombus (n=1). Surgical thrombectomy and anticoagulation (warfarin and intravenous heparin) was evaluated on Resolution of thrombi and heart failure symptoms. In a 32-year-old woman with peripartum cardiomyopathy, surgical thrombectomy followed by aggressive anticoagulation with intravenous heparin and warfarin successfully resolved recurrent left ventricular apical thrombi without embolism.
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