Population
Sheep with indwelling artery and vein catheters
Comparison
Haemorrhage under pentobarbitone anaesthesia vs Haemorrhage of equivalent blood loss in…
Design
Preclinical
Follow-up
Up to 3 hours post-haemorrhage
Authors
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Anaesthesia markedly amplifies renin response to haemorrhage in sheep; leaves open relevance to conscious states or clinical translation.
Pentobarbitone anaesthesia markedly amplifies the renin secretion response to mild haemorrhage in sheep compared to the conscious state.
Mzail et al. (1986) studied this question.
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