Why the study?
Whether the obesity paradox of lower mortality rates among overweight or obese individuals applies to patients undergoing PCI remains unclear.
Does body mass index affect total cardiovascular events in patients with coronary artery disease undergoing percutaneous coronary intervention?
Cohort (n=5,427)
Does body mass index affect total cardiovascular events in patients with coronary artery disease undergoing percutaneous coronary intervention?
Supports obesity paradox post-PCI; hypothesis-generating and should not yet change weight management practice.
Background: The obesity paradox refers to lower mortality rates among overweight or obese individuals within certain populations. However, whether this paradox is applicable to patients undergoing percutaneous coronary intervention (PCI) remains unclear. Methods: A total of 5,427 patients with coronary artery disease (CAD) who underwent successful PCI between 2005 and 2015 were enrolled. The association between body mass index (BMI) and future adverse cardiovascular events post PCI was analyzed. The study endpoints encompassed total cardiovascular (CV) events, including cardiac death, nonfatal myocardial infarction (MI), ischemic stroke, and hospitalization for congestive heart failure (CHF). Results: . Conclusions: ).
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Lin et al. (2025) conducted a cohort in Coronary artery disease (CAD) (n=5,427). Body mass index (BMI) was evaluated on Total cardiovascular (CV) events, including cardiac death, nonfatal myocardial infarction (MI), ischemic stroke, and hospitalization for congestive heart failure (CHF).
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