Key result
A 3-day self blood pressure measurement protocol identified uncontrolled hypertension with an optimal cut-off of 135.5/83 mmHg, though misclassification was significantly more likely in males, older patients, and those with chronic kidney disease.
Why the study?
Optimal cut-off points and factors affecting the precision of a 3-day self blood pressure measurement protocol compared with 24-h ambulatory blood pressure monitoring needed to be established.
Does a 3-day self blood pressure measurement protocol accurately classify hypertension control compared to 24-hour ambulatory blood pressure monitoring in hypertensive patients?
Cross-Sectional (n=153)
No
Does a 3-day self blood pressure measurement protocol accurately classify hypertension control compared to 24-hour ambulatory blood pressure monitoring in hypertensive patients?
Answers are grounded in this paper and cite their sources.
A 3-day self blood pressure measurement protocol is a valid tool for assessing hypertension control, though its accuracy is reduced in males, older patients, those with low income, and those with chronic kidney disease.
BACKGROUND: Improving clinical practice aimed at controlling hypertension is a pending issue in health systems. One of the methods currently used for this purpose is self blood pressure measurement (SBPM) whose use increases every day. The aims of this study are to establish the optimal cut-off point for the 3-day SMBP protocol and to identify factors that could affect the precision of the 3-day SMBP protocol using 24-h ambulatory blood pressure monitoring (ABPM) as a reference. METHOD: This is a cross-sectional descriptive study to validate a diagnostic test performed by a primary care team in Murcia, Spain. A total of 153 hypertensive patients under 80 years of age who met the inclusion criteria were evaluated. ABPM was performed for 24 h. The SBPM protocol consisted of recording 2 measurements in the morning and 2 at night for 3 days. RESULTS: The cut-off point for SBP was set at 135 mmHg (sensitivity: 80.39%, specificity: 74.19%), and for DBP, it was set at 83 mmHg (sensitivity: 76.48%, specificity: 84.89%), which yielded the highest combined sensitivity and specificity. After carrying out the validation study with the new figures, we proceeded to establish which socio-demographic factors prevented a correct classification of patients. These errors were more common in male patients for the assessments of both DBP (OR = 2.4) and SBP (OR = 2.5); hypertensive patients with age < 67,5 years (OR = 1,5); having no work activity (OR = 3,6) and with concomitant chronic kidney disease (CKD) (OR = 5.0). CONCLUSION: Being male, older than 67.5 years, with CKD or with no work activity increases the probability of being misclassified for hypertension during follow-up as assessed by SBPM over 3 days. TRIAL REGISTRATION: This study was approved by the research ethics committee of the University of Murcia under registration number 1018/2015.
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León-Robert et al. (2019) conducted a cross-sectional in Hypertension (n=153). 3-day self blood pressure measurement (SBPM) protocol vs. 24-h ambulatory blood pressure monitoring (ABPM) was evaluated on Optimal diagnostic cut-off point for uncontrolled hypertension. A 3-day self blood pressure measurement protocol identified uncontrolled hypertension with an optimal cut-off of 135.5/83 mmHg, though misclassification was significantly more likely in males, older patients, and those with chronic kidney disease.
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