Key result
Systolic time intervals, specifically LVPET and the PET/LVET ratio, showed a significant linear correlation with QRS duration and dyssynchrony index (r=0.4, P<0.01).
Why the study?
To evaluate systolic time intervals as simple echocardiographic measures of LV systolic performance and examine their relationship to LV intraventricular dyssynchrony assessed by speckle tracking in dilated cardiomyopathy.
Do systolic time intervals correlate with intraventricular dyssynchrony in patients with dilated cardiomyopathy?
Observational (n=153)
Do systolic time intervals correlate with intraventricular dyssynchrony in patients with dilated cardiomyopathy?
Systolic time intervals, specifically LVPET and the PET/LVET ratio, correlate significantly with intraventricular dyssynchrony and may serve as simple echocardiographic indicators in patients with dilated cardiomyopathy.
May aid noninvasive dyssynchrony assessment; leaves open clinical utility pending prospective validation.
Aim To assess the value of systolic time intervals [as simple echocardiographic parameters of left ventricle (LV) systolic performance] and its relation to intraventricular dyssynchrony (by speckle tracking) of the LV in patients with dilated cardiomyopathy. Patients and methods All the studied individuals were subjected to ECG and transthoracic echocardiography to measure LV dimensions and systolic function by conventional and speckle-tracking echo. Left ventricular pre-ejection time (LVPET), left ventricular ejection time (LVET), and the ratio of LVPET to LVET were also measured (LVPET/LVET). Two-dimensional strain to measure time to peak negative strain value of the LV segments was averaged to calculate TPS-SD. Results The enrolled population were 153 cases, divided into 123 patients and 30 normal individuals. There was a significant lower LV global longitudinal strain % in the patient group. Moreover, insignificant shorter LVET was seen in the patients. LVET had an inversely significant correlation with QRS duration and dyssynchrony index. The LVPET and PET/LVET ratio had a significant linear correlation with QRS duration and dyssynchrony index measured by two-dimensional strain ( r =0.4, P <0.01). Conclusion Systolic time interval can be easily and accurately measured in patients with DCM and may be considered as an indicator for presence of LV intraventricular dyssynchrony.
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Asmaa Hasan (2021) conducted an observational in Dilated cardiomyopathy (n=153). Systolic time intervals (LVPET, LVET, LVPET/LVET ratio) vs. Normal individuals was evaluated on Correlation between systolic time intervals and intraventricular dyssynchrony index (r = 0.4, p=<0.01). Systolic time intervals, specifically LVPET and the PET/LVET ratio, showed a significant linear correlation with QRS duration and dyssynchrony index (r=0.4, P<0.01).
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