Key result
Lipoprotein lipase (LPL) plays a central role in energy metabolism and the clearance of triacylglycerol-rich lipoproteins, a process often slowed in metabolic disease due to decreased endothelial LPL.
Design
Review
Authors
Loading...
Endothelial LPL may be a therapeutic target in metabolic disease; leaves open whether its restoration improves outcomes.
This review highlights the central role of lipoprotein lipase and its transporter GPIHBP1 in lipid metabolism and their impairment in metabolic diseases.
Gunilla Olivecrona (2016) conducted a review in Metabolic disease. Lipoprotein lipase (LPL) was evaluated. Lipoprotein lipase (LPL) plays a central role in energy metabolism and the clearance of triacylglycerol-rich lipoproteins, a process often slowed in metabolic disease due to decreased endothelial LPL.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: