Key result
Burdening recent stressful life events were associated with higher emotional distress in symptomatic long QT syndrome mutation carriers (β = 0.35, p < 0.001), but not in asymptomatic carriers.
Why the study?
Does symptomatic status increase emotional distress in long QT syndrome mutation carriers who have experienced recent stressful life events?
Cross-Sectional (n=488)
Does symptomatic status increase emotional distress in long QT syndrome mutation carriers who have experienced recent stressful life events?
Symptomatic long QT syndrome mutation carriers experience significantly higher emotional distress following stressful life events compared to asymptomatic carriers, highlighting the need for psychological support in this subgroup.
May support psychological screening in symptomatic LQTS carriers after stress; hypothesis-generating and leaves open causal effects.
To study emotional distress in symptomatic and asymptomatic long QT syndrome mutation carriers who had experienced a recent stressful life event. The participants were 209 symptomatic and 279 asymptomatic long QT syndrome mutation carriers. Emotional distress was assessed with the Cope questionnaire and stressful life events with the Social Readjustment Rating Scale. Symptomatic long QT syndrome mutation carriers with burdening recent stressful life events reported a higher emotional distress (β = 0.35, p < 0.001), while the asymptomatic did not show such difference (β = 0.13, p = 0.393). Symptomatic long QT syndrome mutation carriers who have experienced stressful life events recently report an increased emotional distress.
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Määttänen et al. (2013) conducted a cross-sectional in Long QT syndrome (n=488). Burdening recent stressful life events vs. Asymptomatic long QT syndrome mutation carriers was evaluated on Emotional distress assessed with the Cope questionnaire (β = 0.35, p=<0.001). Burdening recent stressful life events were associated with higher emotional distress in symptomatic long QT syndrome mutation carriers (β = 0.35, p < 0.001), but not in asymptomatic carriers.
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