Why the study?
Does the combination of estrogen and an AT1 receptor blocker synergistically attenuate neointima formation in mice with vascular injury?
Does the combination of estrogen and an AT1 receptor blocker synergistically attenuate neointima formation in mice with vascular injury?
Estrogen and an AT1 receptor blocker synergistically attenuate vascular remodeling after injury in a mouse model, partly via inhibition of ERK and STAT activity.
Authors
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Low-dose ARB-estrogen synergy attenuates vascular remodeling in mice; leaves open clinical translation to human postmenopausal vascular disease.
Liu et al. (2002) studied this question.
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