Key result
Warfarin therapy in a Turkish cohort of 4,987 adults resulted in a low mean time in therapeutic range of 49.5%, with 20.1% of patients experiencing a bleeding event within a year.
Population
4,987 adult patients in Turkey using warfarin and undergoing regular international normalized ratio monitoring
Design
Cohort
Follow-up
1 year
Authors
Loading...
Suboptimal TTR and high bleeding warrant closer monitoring in similar cohorts; leaves open questions on regional barriers and alternatives.
Cohort (n=4,987)
Yes
In a large Turkish cohort, warfarin therapy was associated with a low mean time in therapeutic range (49.5%) and low patient awareness, highlighting the need for improved patient education and monitoring.
Çelik et al. (2015) conducted a cohort in Patients requiring anticoagulation (mechanical valve, non-valvular atrial fibrillation, other) (n=4,987). Warfarin therapy was evaluated on Time in therapeutic range (TTR). Warfarin therapy in a Turkish cohort of 4,987 adults resulted in a low mean time in therapeutic range of 49.5%, with 20.1% of patients experiencing a bleeding event within a year.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: