Key result
Synthesized derivatives of aspirin, ibuprofen, and salicylic acid achieved appropriate COX-1/COX-2 selectivity as demonstrated by molecular modeling and in vitro studies.
Synthesized analogues of aspirin and ibuprofen demonstrate distinct COX-1/COX-2 selectivity in vitro, providing a basis for future anti-inflammatory drug development.
Aspirin, ibuprofen, and salicylic acid derivatives were synthesized to achieve appropriate COX-1/COX-2 selectivity, with the findings supported by molecular modeling and in vitro studies.
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Kaur et al. (2025) studied this question. Synthesized derivatives of aspirin, ibuprofen, and salicylic acid achieved appropriate COX-1/COX-2 selectivity as demonstrated by molecular modeling and in vitro studies.
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