Key result
Every 0.10 increase in systolic blood pressure coefficient of variation was associated with increased 30-day mortality (OR 2.50; 95% CI 1.60-3.92) and in-hospital renal failure (OR 2.04).
Why the study?
Does increasing perioperative blood pressure variability increase 30-day mortality and in-hospital renal failure in patients undergoing cardiac surgery requiring cardiopulmonary bypass?
Population
3,687 patients undergoing cardiac surgery requiring cardiopulmonary bypass
Design
Cohort
Follow-up
30 days
Authors
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SBP variability may flag high-risk patients; hypothesis-generating and requires prospective trials before practice change.
Cohort (n=3,687)
No
Does increasing perioperative blood pressure variability increase 30-day mortality and in-hospital renal failure in patients undergoing cardiac surgery requiring cardiopulmonary bypass?
Odds Ratio: 2.5 (95% CI 1.6–3.92)
p-value: p=< .0001
Increasing systolic blood pressure variability during cardiac surgery is significantly associated with higher 30-day mortality and in-hospital renal failure.
Jinadasa et al. (2018) conducted a cohort in Cardiac surgery requiring cardiopulmonary bypass (n=3,687). Systolic blood pressure variability (coefficient of variation) was evaluated on 30-day mortality (OR 2.50, 95% CI 1.60-3.92, p=< .0001). Every 0.10 increase in systolic blood pressure coefficient of variation was associated with increased 30-day mortality (OR 2.50; 95% CI 1.60-3.92) and in-hospital renal failure (OR 2.04).
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