Key result
Mean duration of intraoperative systolic blood pressure excursion outside 105-130 mmHg predicted 30-day mortality in CABG patients (OR 1.03 per minute; 95% CI 1.02-1.39; P<0.0001).
Why the study?
Does intraoperative systolic blood pressure variability outside a targeted range predict 30-day mortality in patients undergoing coronary bypass surgery?
Population
7,504 consecutive patients undergoing coronary bypass surgery procedures.
Design
Cohort
Follow-up
30-day
Authors
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May flag elevated 30-day mortality risk during CABG; leaves open whether targeted BP control improves outcomes.
Cohort (n=7,504)
Does intraoperative systolic blood pressure variability outside a targeted range predict 30-day mortality in patients undergoing coronary bypass surgery?
Odds Ratio: 1.03 (95% CI 1.02–1.39)
p-value: p=<0.0001
Intraoperative systolic blood pressure excursions outside the 105-130 mmHg range are significantly associated with increased 30-day mortality in patients undergoing coronary bypass surgery.
Aronson et al. (2010) conducted a cohort in Aortocoronary bypass surgery (n=7,504). Intraoperative systolic blood pressure variability was evaluated on 30-day mortality (OR 1.03, 95% CI 1.02-1.39, p=<0.0001). Mean duration of intraoperative systolic blood pressure excursion outside 105-130 mmHg predicted 30-day mortality in CABG patients (OR 1.03 per minute; 95% CI 1.02-1.39; P<0.0001).
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