Aortic Changes in Experimental Renal Failure

Subtotally nephrectomized rats

Subtotal nephrectomy (experimental renal failure model)

Sham-operated controls

Aortic wall thickness, cross-sectional area of aortic media, total number of vascular smooth muscle cells per unit aortic length, mean cell and nuclear volumes, volume density of elastic fibers, extracellular matrix, vascular smooth muscle cells, and total volumes of these structures per unit of aortic lengthsurrogate