Key result
High 24-hour systolic blood pressure variability was independently associated with a significantly increased risk of poor functional outcome at discharge in patients with acute ischemic stroke (OR 9.65).
Why the study?
The study aimed to evaluate blood pressure variability as a target therapeutic risk factor for poor ischemic stroke outcome by examining its association and population attributable risk.
Does 24-hr blood pressure variability predict poor functional outcome in patients with acute ischemic stroke?
Observational (n=75)
No
Does 24-hr blood pressure variability predict poor functional outcome in patients with acute ischemic stroke?
Odds Ratio: 9.65 (95% CI 3.02–20.1)
Absolute Event Rate: 60.5% vs 16.2%
p-value: p=0.002
24-hour systolic blood pressure variability is a strong independent predictor of poor functional outcome at discharge in acute ischemic stroke patients.
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BPV monitoring may refine acute ischemic stroke prognosis; leaves open whether targeting it improves outcomes.
Khandait et al. (2020) conducted an observational in Acute ischemic stroke (n=75). High 24-hour systolic blood pressure variability (ARV-SBP) vs. Low 24-hour systolic blood pressure variability was evaluated on Poor functional outcome at discharge (Barthel Index score <60) (OR 9.65, 95% CI 3.02-20.1, p=0.002). High 24-hour systolic blood pressure variability was independently associated with a significantly increased risk of poor functional outcome at discharge in patients with acute ischemic stroke (OR 9.65).
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