Key result
The COVID-19 pandemic was associated with increased median door-to-balloon times for STEMI patients (37 minutes in 2019 vs 53 minutes in 2020 and 48 minutes in 2021; P<0.001).
Why the study?
Previous studies documented a negative impact of the COVID-19 pandemic on emergent percutaneous treatment of STEMI, but few had examined the recovery of healthcare systems in restoring prepandemic care.
Does the COVID-19 pandemic worsen treatment times and clinical outcomes in patients with STEMI?
Observational (n=789)
No
Does the COVID-19 pandemic worsen treatment times and clinical outcomes in patients with STEMI?
Absolute Event Rate: 53% vs 37%
p-value: p=< .001
The COVID-19 pandemic was associated with worsened STEMI treatment times and increased late presentations, and despite improving treatment times in 2021, in-hospital mortality remained elevated.
STEMI systems should prepare for care delays in future crises; observational data leaves open sustained mortality effects.
BACKGROUND: Previous studies have documented a negative impact of the COVID-19 pandemic on emergent percutaneous treatment of patients with ST-segment elevation myocardial infarction (STEMI), but few have examined recovery of healthcare systems in restoring prepandemic STEMI care. METHODS: Retrospective analysis was performed of data from 789 patients with STEMI from a large tertiary medical center treated with percutaneous coronary intervention between January 1, 2019, and December 31, 2021. RESULTS: For patients with STEMI presenting to the emergency department, median time from door to balloon was 37 minutes in 2019, 53 minutes in 2020, and 48 minutes in 2021 (P < .001), whereas median time from first medical contact to device changed from 70 to 82 to 75 minutes, respectively (P = .002). Treatment time changes in 2020 and 2021 correlated with median emergency department evaluation time (30 to 41 to 22 minutes, respectively; P = .001) but not median catheterization laboratory revascularization time. For transfer patients, median time from first medical contact to device changed from 110 to 133 to 118 minutes, respectively (P = .005). In 2020 and 2021, patients with STEMI had greater late presentation (P = .028) and late mechanical complications (P = .021), with nonsignificant increases in yearly in-hospital mortality (3.6% to 5.2% to 6.4%; P = .352). CONCLUSION: COVID-19 was associated with worsening STEMI treatment times and outcomes in 2020. Despite improving treatment times in 2021, in-hospital mortality had not decreased in the setting of a persistent increase in late patient presentation and associated STEMI complications.
No takes yet. Share an insight, caveat, or question.
Ali et al. (2023) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=789). COVID-19 pandemic (2020-2021) vs. Pre-pandemic period (2019) was evaluated on Median time from door to balloon for patients presenting to the emergency department (minutes) (p=< .001). The COVID-19 pandemic was associated with increased median door-to-balloon times for STEMI patients (37 minutes in 2019 vs 53 minutes in 2020 and 48 minutes in 2021; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: