Key result
Elevated baseline NT-proBNP was an independent predictor of cardiovascular and all-cause mortality in incident hemodialysis patients, adding prognostic value over traditional risk factors.
Why the study?
Do elevated baseline cardiac biomarkers (NT-proBNP, cTnT, hsCRP) predict cardiovascular and all-cause mortality in incident hemodialysis patients?
Cohort (n=864)
Do elevated baseline cardiac biomarkers (NT-proBNP, cTnT, hsCRP) predict cardiovascular and all-cause mortality in incident hemodialysis patients?
NT-proBNP provides significant added prognostic value over traditional risk factors for predicting cardiovascular and all-cause mortality in incident hemodialysis patients.
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May aid mortality risk stratification in incident hemodialysis; extends observational data but leaves therapeutic implications open.
Oh et al. (2014) conducted a cohort in End-stage renal disease on incident hemodialysis (n=864). Elevated baseline NT-proBNP vs. Low baseline NT-proBNP (below median) was evaluated on Cardiovascular and all-cause mortality. Elevated baseline NT-proBNP was an independent predictor of cardiovascular and all-cause mortality in incident hemodialysis patients, adding prognostic value over traditional risk factors.
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