Key result
In dialysis patients, NT-pro-BNP was significantly associated with increased all-cause mortality (HR 1.585; 95% CI 1.160-20165; P=0.004), providing greater prognostic information than troponins.
Why the study?
Do cardiac biomarkers (TnT, TnI, BNP, NT-pro-BNP) predict all-cause mortality in dialysis patients?
Cohort (n=143)
No
Do cardiac biomarkers (TnT, TnI, BNP, NT-pro-BNP) predict all-cause mortality in dialysis patients?
Hazard Ratio: 1.585 (95% CI 1.16–20165)
p-value: p=0.004
In dialysis patients, NT-pro-BNP is an independent predictor of all-cause mortality and provides greater prognostic information than troponins.
No takes yet. Share an insight, caveat, or question.
May enhance risk stratification in dialysis patients; leaves open whether NT-pro-BNP improves models or guides therapy.
Hickman et al. (2009) conducted a cohort in end-stage renal disease on dialysis (n=143). Cardiac biomarkers (NT-pro-BNP, TnT, TnI, BNP) was evaluated on all-cause mortality (HR 1.585, 95% CI 1.160-20165, p=0.004). In dialysis patients, NT-pro-BNP was significantly associated with increased all-cause mortality (HR 1.585; 95% CI 1.160-20165; P=0.004), providing greater prognostic information than troponins.
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