Key result
Midazolam premedication significantly reduced systolic blood pressure upon entering the operating room in hypertensive patients compared to no premedication (131.6 vs 154.3 mmHg, p<0.001), though it also lowered oxygen saturation.
Why the study?
Does midazolam premedication reduce excessive blood pressure rise upon entering the operating room in patients with hypertension?
Observational (n=159)
Does midazolam premedication reduce excessive blood pressure rise upon entering the operating room in patients with hypertension?
Absolute Event Rate: 131.6% vs 154.3%
p-value: p=<0.001
Midazolam premedication effectively blunts the excessive rise in systolic blood pressure upon entering the operating room in hypertensive patients, though it requires monitoring for mild decreases in oxygen saturation.
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Tetsu et al. (2014) conducted an observational in Hypertension in patients undergoing surgery (n=159). Midazolam premedication vs. No premedication was evaluated on Systolic blood pressure upon entering the operating room in hypertensive patients (p=<0.001). Midazolam premedication significantly reduced systolic blood pressure upon entering the operating room in hypertensive patients compared to no premedication (131.6 vs 154.3 mmHg, p<0.001), though it also lowered oxygen saturation.
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