Key result
High-intensity cycling at 120% of lactate threshold increased nitric oxide (7.2 to 9.5 µM) and decreased systolic blood pressure (126.6 to 118.7 mmHg) in individuals with type 2 diabetes (p<0.05).
Why the study?
Does high intensity cycling above lactate threshold improve nitric oxide release and post-exercise blood pressure reduction in individuals with type-2 diabetes?
Does high intensity cycling above lactate threshold improve nitric oxide release and post-exercise blood pressure reduction in individuals with type-2 diabetes?
High-intensity cycling above the lactate threshold is effective for increasing nitric oxide release and reducing post-exercise blood pressure in individuals with type 2 diabetes.
May inform exercise prescriptions for type 2 diabetes; leaves open whether chronic training improves cardiovascular outcomes.
The purposes of this study were to analyze and compare the effects of exercise performed in different intensities, above and below lactate threshold (LT) on post-exercise blood pressure (BP) and nitric oxide (NO) responses in individuals with type 2 diabetes (T2D). For this, 11 T2D underwent the following sessions: 1) control session; 2) 20-min of moderate cycling (80% LT); and 3) 20-min of high intensity cycling (120%LT) on a cycle ergometer. Plasma NO and BP measurements were carried out at rest and at 15 and 45 min of post-sessions. When compared to rest, only the exercise session performed at 120%LT elicited an increase of NO (from 7.2 to 9.5 µM, p<0.05), as well as a decrease in systolic BP (from 126.6±7.9 to 118.7±3.9 mmHg, p<0.05) during the post-exercise period. In conclusion, the results suggest that NO release and post-exercise BP decrease are intensity-dependent for individuals with T2D.
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Asano et al. (2013) studied Type 2 diabetes (n=11). High intensity cycling (120% lactate threshold) vs. Control session and moderate cycling (80% lactate threshold) was evaluated on Post-exercise blood pressure and nitric oxide responses (p=<0.05). High-intensity cycling at 120% of lactate threshold increased nitric oxide (7.2 to 9.5 µM) and decreased systolic blood pressure (126.6 to 118.7 mmHg) in individuals with type 2 diabetes (p<0.05).
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