A Golden Gate: Alkynylspirocyclopropanes served as a template for the development of gold-catalyzed hydride transfer from unactivated C(sp3)H bonds to electronically neutral alkynes. A variety of interesting carbocyclic structures can be accessed selectively with the appropriate choice of the reaction conditions. Mechanistic studies support a sequential gold-catalyzed cleavage of CH and CC bonds.
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Barluenga et al. (2012) studied this question.
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