What question did this study set out to answer?

To evaluate a soft inversion recovery fluid attenuation sequence using prolonged inversion pulses for cerebrospinal fluid suppression in brain sodium MRI.

October 10, 2005Magnetic Resonance in MedicineOpen Access

In vivo sodium magnetic resonance imaging of the human brain using soft inversion recovery fluid attenuation

View Full Paper

Ask AI

Bookmark

To evaluate a soft inversion recovery fluid attenuation sequence using prolonged inversion pulses for cerebrospinal fluid suppression in brain sodium MRI.
Conducted numerical simulations, phantom validations, and in vivo scans on a 4.7 T MRI system in five healthy volunteers.
Implemented a 10-ms rectangular inversion pulse, compared with a standard 1-ms pulse, to lower radiofrequency power deposition and enable shorter repetition times.
Acquired sodium brain images in an 11.1-minute scan time with a voxel volume of 0.25 cm³.
Simulations and phantom experiments demonstrated a marked increase in signal-to-noise ratio (SNR) using the 10-ms pulse over the 1-ms pulse.
Cerebrospinal fluid SNR was suppressed to 23% of brain tissue SNR (down from its typical baseline of approximately three times higher than brain tissue), while brain tissue attained an average SNR of 17.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Imaging study demonstrates cerebrospinal fluid suppression via soft inversion recovery in healthy volunteers, indicating improved intracellular sodium signal visualization.

Cite This Study

Stobbe et al. (2005) studied this question.

synapsesocial.com/papers/6a77750f7ecc675f86ae6ebc https://doi.org/10.1002/mrm.20696

View Full Paper

Ask AI

Bookmark

Implication

Imaging study demonstrates cerebrospinal fluid suppression via soft inversion recovery in healthy volunteers, indicating improved intracellular sodium signal visualization.

In vivo sodium magnetic resonance imaging of the human brain using soft inversion recovery fluid attenuation

Key Points

Discussion

Implication

Cite This Study

In vivo sodium magnetic resonance imaging of the human brain using soft inversion recovery fluid attenuation

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider