Key result
Childhood cancer survivors demonstrated significantly altered autonomic nervous system activity and a higher spontaneous heart rate compared with healthy controls (67 vs. 60 bpm, p=0.001).
Why the study?
Does childhood cancer survival alter autonomic nervous system activity compared to healthy controls?
Population
51 long-term childhood cancer survivors diagnosed before 15 years of age between 1987 and 1992, and healthy…
Design
Cohort
Authors
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May warrant ANS screening in survivors; leaves open whether HRV predicts late cardiovascular events.
Case-Control
Does childhood cancer survival alter autonomic nervous system activity compared to healthy controls?
Absolute Event Rate: 67% vs 60%
p-value: p=0.001
Long-term childhood cancer survivors exhibit significant autonomic nervous system dysfunction, highlighting the potential value of autonomic screening and physical activity interventions in this population.
Berger et al. (2018) conducted a case-control in Childhood cancer survivors. History of childhood cancer vs. Healthy controls was evaluated on Spontaneous heart rate (beats per minute) (p=0.001). Childhood cancer survivors demonstrated significantly altered autonomic nervous system activity and a higher spontaneous heart rate compared with healthy controls (67 vs. 60 bpm, p=0.001).
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