Why the study?
Does chronic thyroid hormone treatment induce and stabilize the adult myosin phenotype in cardiac and skeletal muscle of dwarf mice?
Population
mouse mutant dwarf
Design
Preclinical
Follow-up
at least five weeks after the last injection
Authors
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Differential thyroxine responses in murine cardiac versus skeletal muscle; leaves open applicability to human thyroid hormone therapy.
Does chronic thyroid hormone treatment induce and stabilize the adult myosin phenotype in cardiac and skeletal muscle of dwarf mice?
Cardiac and skeletal muscles in dwarf mice respond differently to thyroxine treatment and withdrawal regarding myosin phenotype expression.
Prulière et al. (1989) studied this question.
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