Key result
Endovascular renal sympathetic denervation was initially proposed as an empirical treatment for resistant hypertension based on porcine models.
Discusses the historical context and evolution of endovascular renal sympathetic denervation techniques for resistant hypertension.
A decade ago, when endovascular renal sympathetic denervation (RDN) using radiofrequency energy was first proposed as a treatment of resistant hypertension,1 the strategy of renal nerve ablation, by that time using the mono-electrode Simplicity catheter, was almost purely empirical, based on porcine model. It was advised to distribute a few ablation points along a spiral path to increase RDN efficacy, while avoiding both circumferential nerve destruction and side branch approach, considered as potentially dangerous. [...]
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Persu et al. (2020) conducted an editorial in resistant hypertension. endovascular renal sympathetic denervation (RDN) was evaluated. Endovascular renal sympathetic denervation was initially proposed as an empirical treatment for resistant hypertension based on porcine models.
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