Recurrence of pulmonary embolism during anticoagulant treatment: a prospective study.
Why the study?
Does adjusted anticoagulant treatment prevent early recurrence of pulmonary embolism in patients with concurrent proximal deep vein thrombosis?
Population
50 patients with angiographically proved pulmonary embolism plus phlebographically proved proximal deep vein…
Design
Cohort
Follow-up
15 days
Authors
Discussion
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Member takes
Implication
May support adjusted anticoagulation to avert early PE recurrence with proximal DVT; leaves open need for randomized confirmation.
Structured PICO
Does adjusted anticoagulant treatment prevent early recurrence of pulmonary embolism in patients with concurrent proximal deep vein thrombosis?
P
Population
50 patients with angiographically proved pulmonary embolism plus phlebographically proved proximal deep vein thrombosis
I
Intervention
Adjusted anticoagulant treatment for the first 15 days with clinical and scintigraphic surveillance (perfusion lung scans initially and on days 3, 7, and 15)
O
Outcome
Early recurrence of pulmonary embolism during the first 15 days of treatmenthard clinical
Adjusted anticoagulant treatment is highly effective (96%) at preventing early recurrence of pulmonary embolism in high-risk patients with concurrent proximal DVT.
Cite This Study
Girard et al. (1987) studied this question.