Key result
A sirolimus-eluting stent with a bioabsorbable coating significantly reduced in-segment restenosis at 6 months compared to a bare metal stent (17.4% vs 60%, p<0.0001).
Why the study?
Does a sirolimus-eluting stent with a bioabsorbable coating reduce late lumen loss and in-segment restenosis compared to a bare metal stent in patients with chronic total coronary occlusions?
RCT (n=95)
Does a sirolimus-eluting stent with a bioabsorbable coating reduce late lumen loss and in-segment restenosis compared to a bare metal stent in patients with chronic total coronary occlusions?
Absolute Event Rate: 17.4% vs 60%
p-value: p=<0.0001
A sirolimus-eluting stent with a bioabsorbable coating significantly reduced restenosis and target vessel revascularization compared to a bare metal stent in chronic total occlusions over 24 months.
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Supports bioabsorbable sirolimus-eluting stents in CTO PCI; extends randomized evidence to complex lesions.
Reifart et al. (2010) conducted an RCT in chronic total coronary occlusions (CTO) (n=95). sirolimus eluting stent with a bioabsorbable coating (SES) vs. bare metal stent (BMS) was evaluated on late lumen loss (LLL) and in-segment restenosis (ISR) after six months (p=<0.0001). A sirolimus-eluting stent with a bioabsorbable coating significantly reduced in-segment restenosis at 6 months compared to a bare metal stent (17.4% vs 60%, p<0.0001).
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