Why the study?
Do major classes of blood pressure-lowering drugs reduce cardiovascular morbidity and mortality in hypertensive patients in Latin America?
Population
Hypertensive patients in Latin America
Comparison
All major classes of blood pressure-lowering drugs vs Placebo or other classes of blood…
Design
Guideline
Authors
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May support lowest-cost antihypertensive selection; leaves open need for updated implementation trials.
Do major classes of blood pressure-lowering drugs reduce cardiovascular morbidity and mortality in hypertensive patients in Latin America?
The Latin American Society of Hypertension recommends that all major classes of antihypertensive drugs be made available, as they offer comparable cardiovascular protection, allowing selection based on cost-effectiveness.
Coca et al. (2017) conducted a review in Hypertension. Antihypertensive drugs vs. Placebo or other classes was evaluated. All major classes of blood pressure-lowering drugs reduce major cardiovascular outcomes compared with placebo and have comparable efficacy, suggesting selection should be based on lowest prices.
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