Key result
The quick Pitt score had moderate prognostic accuracy (AUROC 0.692) and performed worse than qSOFA (AUROC 0.832) and SOFA (AUROC 0.806) scores for predicting 30-day mortality in patients with UTI.
Why the study?
The study aimed to compare the new prognostic quick Pitt (qPitt) score with quick SOFA (qSOFA) and SOFA for scoring severity in patients with urinary tract infection.
Does the qPitt score improve prediction of 30-day mortality compared to qSOFA and SOFA in patients with community-acquired UTI?
Observational (n=382)
No
Does the qPitt score improve prediction of 30-day mortality compared to qSOFA and SOFA in patients with community-acquired UTI?
Absolute Event Rate: 0.692% vs 0.832%
p-value: p=0.010
Quick Pitt (qPitt), which includes temperature, systolic blood pressure, respiratory rate, cardiac arrest, and mental status, is a new prognostic score derived from the Pitt Bacteremia score. The aim of our study is to compare qPitt with quick SOFA (qSOFA) and SOFA for scoring of severity in patients with urinary tract infection (UTI). Prospective observational study of patients diagnosed with UTI. Area under the ROC curve, sensibility, and specificity to predict 30-day mortality were calculated for qPitt, qSOFA and SOFA and compared. 382 UTI cases were analyzed. Thirty-day mortality (18.8% vs. 5.9%, p < 0.001) and longer hospital stay (6 [1-11] vs. 4 [1-7] days, p < 0.001) were associated with qPitt ≥ 2. However, qPitt had a worse performance to predict 30-day mortality compared to qSOFA and SOFA (AUROC 0.692 vs. 0.832 and 0.806, respectively, p = 0.010 and p = 0.041). The sensitivity of qPitt was lower than the sensitivity of qSOFA and SOFA (70.45 vs. 84.09 for both qSOFA and SOFA, p < 0.001), with a specificity lower than qSOFA and similar to SOFA (60.36 vs. 82.25 and 63.61, p < 0.001 and p = 0.742, respectively). Quick Pitt had moderate prognostic accuracy and performed worse than qSOFA and SOFA scores for predicting mortality in patients with UTI.
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Madrazo et al. (2022) conducted an observational in Urinary tract infection (n=382). quick Pitt (qPitt) score vs. qSOFA and SOFA scores was evaluated on Prediction of 30-day mortality (AUROC) (95% CI 0.605-0.779, p=0.010). The quick Pitt score had moderate prognostic accuracy (AUROC 0.692) and performed worse than qSOFA (AUROC 0.832) and SOFA (AUROC 0.806) scores for predicting 30-day mortality in patients with UTI.
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