December 1, 2001American Journal of Hypertension
Sibling correlation of left ventricular mass and geometry in hypertensive African Americans and whites: the HyperGEN study
Why the study?
Does the familial correlation of left ventricular mass and geometry differ between hypertensive African American and white siblings?
Population
1,664 African American and white hypertensive siblings, aged 23 to 87 years, recruited from four field…
Design
Cross-sectional
Authors
Discussion
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Implication
Racial differences in sibling LV mass correlations may exist in hypertension; hypothesis-generating for genetic influences on LVH and needs confirmation.
Structured PICO
Does the familial correlation of left ventricular mass and geometry differ between hypertensive African American and white siblings?
P
Population
1,664 African American and white hypertensive siblings, aged 23 to 87 years, recruited from four field centers as part of the HyperGEN study.
O
Outcome
Sibling correlation of left ventricular (LV) mass and relative wall thickness (RWT)surrogate
The genetic influence on left ventricular hypertrophy and geometric remodeling appears to differ between African American and white hypertensive patients.
Cite This Study
Donna K. Arnett (2001) studied this question.