December 1, 1994AJP Heart and Circulatory Physiology

Influence of cardiac output distribution on cardiac filling pressure during rest and dynamic exercise in dogs

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Population

6 dogs with surgically produced atrioventricular block and implanted blood flow transducers on the ascending…

Design

Preclinical

Authors

DSDon D. SheriffUniversity of Iowa XZXuezhe ZhouUniversity of Washington

Discussion

Member takes

Implication

No immediate clinical implications in humans; leaves open translation of intensity-dependent CO redistribution from canine models.

Structured PICO

Population

6 dogs with surgically produced atrioventricular block and implanted blood flow transducers on the ascending aorta and terminal aorta

Intervention

Reduction of cardiac output by lowering ventricular pacing rate at rest and during graded treadmill exercise (2 and 4 miles/h at 0% grade)

Outcome

Fraction of cardiac output directed to muscle (MBF/CO) and its relationship with right atrial pressuresurrogate

In a canine model, the distribution of cardiac output to muscle depends on exercise intensity and cardiac output levels, influencing the relationship between cardiac output and right atrial pressure.

Cite This Study

Sheriff et al. (1994) studied this question.

synapsesocial.com/papers/6a77b6767ecc675f86ae9588 https://doi.org/10.1152/ajpheart.1994.267.6.h2378

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Influence of cardiac output distribution on cardiac filling pressure during rest and dynamic exercise in dogs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Influence of cardiac output distribution on cardiac filling pressure during rest and dynamic exercise in dogs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider