Pressure gradient and blood flow in human arm veins. -A proposed explanation of the pumping mechanism-.

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Population

Patients with congestive heart failure and other subjects undergoing venous pressure and flow measurements

Comparison

Intravenous lidocaine, supine leg exercise, and… vs Saline injection and baseline resting state

Authors

Discussion

Small human study; leaves open lidocaine modulation of an active venous pump and should not change practice.

Population

Patients with congestive heart failure and other subjects undergoing venous pressure and flow measurements

Intervention

Intravenous lidocaine (1-26 mg), supine leg exercise, and Valsalva's maneuver

Comparator

Saline injection and baseline resting state

Outcome

Peripheral venous pressure (Pv), periphero-central pressure gradient (P-C PG), and peripheral venous blood flow velocity (PVBFV)surrogate

The study provides physiological evidence suggesting an active pumping mechanism in superficial human arm veins that can be modulated by lidocaine.

Watanabe et al. (1984) studied this question.

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