Why the study?
Does verapamil reduce postinfarction ischemia and ventricular arrhythmias in patients after an acute myocardial infarction?
Population
Patients after an acute myocardial infarction
Comparison
Verapamil (long-term treatment) vs Placebo
Design
Review, Randomized to long-term treatment with placebo or verapamil
Follow-up
18 months
Authors
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May reduce post-MI ischemia; hypothesis-generating and should not yet change practice.
Does verapamil reduce postinfarction ischemia and ventricular arrhythmias in patients after an acute myocardial infarction?
Verapamil reduces postinfarction ischemia and prevents the increase in ventricular ectopic beats, which may explain its benefit in reducing major events post-myocardial infarction.
Vaage-Nilsen et al. (1991) studied this question.
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