Population
Rabbits with one intact and one denervated kidney
Comparison
Treadmill exercise of various intensities, with… vs Intact versus denervated kidney responses
Design
Preclinical
Follow-up
up to 2 minutes of exercise
Authors
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Alpha-adrenergic renal nerve activation drives early exercise vasoconstriction in this model; extends mechanistic insights but leaves open human translation.
Renal vasoconstriction during early dynamic exercise in rabbits is primarily mediated by renal nerves via alpha-adrenergic receptor activation.
Mueller et al. (1998) studied this question.
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