May 1, 1991Journal of Applied Physiology

Renal neurohormonal and vascular responses to dynamic exercise in humans

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Why the study?

Does graded dynamic exercise increase renal vascular resistance and renal sympathetic nerve activity in healthy male volunteers?

Population

8 healthy male volunteers

Comparison

Graded supine dynamic exercise vs Rest

Design

Other

Authors

BTBo TidgrenKarolinska University Hospital PHPaul HjemdahlPreventive Cardiology ETElvar TheodorssonLinköping University

Discussion

Member takes

Implication

Supports exercise-induced renal sympathetic activation in healthy men; leaves open its clinical relevance in cardiovascular disease.

Structured PICO

Does graded dynamic exercise increase renal vascular resistance and renal sympathetic nerve activity in healthy male volunteers?

Population

8 healthy male volunteers

Intervention

Graded supine dynamic exercise (30, 60, and 80-90% of maximal physical capacity, i.e., work loads of 69, 132, and 188 W)

Comparator

Rest

Outcome

Renal vascular resistance (RVR) and renal sympathetic nerve activity (assessed by the renal venous overflow of norepinephrine)surrogate

Dynamic exercise is a potent stimulus for renal nerve activation in humans, contributing to increased renal vascular resistance directly via norepinephrine and indirectly via renin-mediated ANG II formation.

Cite This Study

Tidgren et al. (1991) studied this question.

synapsesocial.com/papers/6a86f1e7540b033b21beff2d https://doi.org/10.1152/jappl.1991.70.5.2279

View Full Paper

Ask AI

Bookmark

Renal neurohormonal and vascular responses to dynamic exercise in humans

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Renal neurohormonal and vascular responses to dynamic exercise in humans

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider