Dynamic responses of active and inactive renin and plasma norepinephrine during exercise in normal man.
Why the study?
Does graded exercise alter active and inactive renin and plasma norepinephrine levels in healthy subjects?
Population
5 healthy subjects
Design
Other
Authors
Discussion
Loading...
Member takes
Implication
Supports sympathetic involvement in exercise renin activation; hypothesis-generating for neurohormonal mechanisms and should not yet change practice.
Structured PICO
Does graded exercise alter active and inactive renin and plasma norepinephrine levels in healthy subjects?
P
Population
5 healthy subjects
I
Intervention
Graded exercise on bicycle ergometer at three different loads (50, 70, and 100% of maximal oxygen uptake)
O
Outcome
Levels of active and inactive plasma renin, plasma angiotensin II, and plasma norepinephrinesurrogate
Graded exercise increases active plasma renin and norepinephrine, suggesting sympathetic nervous system involvement in renin activation.
Cite This Study
Fujita et al. (1982) studied this question.