July 1, 1987Journal of Applied Physiology
Plasma renin system during exercise in normal men
Why the study?
How does exercise intensity affect plasma renin activity, angiotensin II, and aldosterone in healthy men?
Population
43 healthy male volunteers with 24-h urinary sodium excretion ranging from 10 to 250 mmol
Comparison
Bicycle ergometry vs Rest
Design
Other
Authors
Discussion
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Implication
Peak exercise ANG II and aldosterone responses should not yet alter clinical guidance; hypothesis-generating for RAAS dynamics in healthy men.
Structured PICO
How does exercise intensity affect plasma renin activity, angiotensin II, and aldosterone in healthy men?
P
Population
43 healthy male volunteers with 24-h urinary sodium excretion ranging from 10 to 250 mmol
I
Intervention
Bicycle ergometry (light, moderate, and peak exercise)
C
Comparator
Rest
O
Outcome
Changes in plasma renin activity (PRA), angiotensin II (ANG II), and aldosterone (Aldo)surrogate
Exercise intensity differentially activates components of the renin-angiotensin-aldosterone system, with peak exercise causing a disproportionate rise in angiotensin II compared to renin and aldosterone.
Cite This Study
Staessen et al. (1987) studied this question.