Why the study?
How do plasma levels of ANP, AII, and aldosterone respond to exercise in normotensive and hypertensive patients with chronic glomerulonephritis compared to controls?
Population
16 normotensive and 9 hypertensive patients with chronic glomerulonephritis, and 18 control subjects
Comparison
Exercise test vs Control subjects and supine rest conditions
Design
Cross-sectional
Authors
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Blunted post-exercise ANP rise in hypertensive glomerulonephritis patients should not change practice; leaves open mechanisms and prognostic relevance for prospective study.
How do plasma levels of ANP, AII, and aldosterone respond to exercise in normotensive and hypertensive patients with chronic glomerulonephritis compared to controls?
Patients with chronic glomerulonephritis and relatively well-preserved renal function do not have major abnormalities of ANP at rest or during exercise, though normotensive patients show a slightly higher ANP increase after exercise compared to controls.
Danielsen et al. (1988) studied this question.
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