This review summarizes the prevalence, pathophysiology, and medical strategies for left ventricular structural and functional abnormalities in patients with chronic uremia.
Does not alter management of uremic cardiomyopathy; leaves open optimal strategies pending prospective trials.
Left ventricular (LV) structure and function abnormalities are frequent in individuals with chronic uraemia; these disorders are at increased risk of cardiovascular and overall morbidity and mortality in the pre-dialyzed population, during dialysis treatment and in renal transplant recipients. This review will attempt to summarize current knowledge of the prevalence, pathophysiological mechanisms of LV disease in chronic uraemia and to discuss useful medical strategies in this population.
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Dyadyk et al. (1999) studied this question.
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