What question did this study set out to answer?

To evaluate the feasibility of high-gamma electrocorticographic real-time functional mapping for language localization in pediatric epilepsy surgery and determine its correlation with postsurgical language outcomes.

July 4, 2014Journal of Neurosurgery PediatricsOpen Access

Real-time functional mapping: potential tool for improving language outcome in pediatric epilepsy surgery

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Authors

MKMilena KorostenskajaUniversity of California, San Diego PCPo-Ching ChenNeuroscience Institute CSChristine M. SalinasNational Institutes of Health

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Implication

Case report reveals real-time functional mapping accurately localizes language cortex in a pediatric epilepsy patient, suggesting its potential to prevent postsurgical language deficits.

Key Points

To evaluate the feasibility of high-gamma electrocorticographic real-time functional mapping for language localization in pediatric epilepsy surgery and determine its correlation with postsurgical language outcomes.
Conducted a case report in a pediatric epilepsy patient undergoing surgical evaluation.
Compared high-gamma frequency band electrocorticography-based real-time functional mapping (RTFM) to gold-standard electrical cortical stimulation mapping (ESM) using next-neighbor spatial analysis.
Tracked postsurgical language deficits following cortical resection of identified language areas.
RTFM achieved 75% sensitivity and 90% specificity for language localization compared with ESM in a next-neighbor analysis.
RTFM identified language-related activation in expressive cortex that was not detected by ESM; surgical resection of these areas coincided with observed postsurgical expressive language deficits.

Cite This Study

Korostenskaja et al. (2014) studied this question.

synapsesocial.com/papers/6a77cc2d7d04941475ae71d4 https://doi.org/10.3171/2014.6.peds13477

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Implication

Case report reveals real-time functional mapping accurately localizes language cortex in a pediatric epilepsy patient, suggesting its potential to prevent postsurgical language deficits.

Real-time functional mapping: potential tool for improving language outcome in pediatric epilepsy surgery

Discussion

Member takes

Implication

Key Points

Cite This Study

Real-time functional mapping: potential tool for improving language outcome in pediatric epilepsy surgery

Discussion

Member takes

Implication

Key Points

Cite This Study

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