What question did this study set out to answer?

To evaluate the CortiQ real-time functional mapping (RTFM) system in patients undergoing epilepsy surgery and compare its accuracy against electrical cortical stimulation mapping (ESM) and functional magnetic resonance imaging (fMRI).

March 10, 2015Journal of Clinical Neurophysiology

CortiQ-based Real-Time Functional Mapping for Epilepsy Surgery

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Authors

CKChristoph KapellerGuger Technologies (Austria)MKMilena KorostenskajaUniversity of California, San Diego RPRobert PruecklJohannes Kepler University of Linz

Discussion

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Implication

Observational study reveals strong concordance between CortiQ real-time mapping, electrical stimulation, and fMRI in intractable epilepsy, highlighting a flexible tool for surgical guidance.

Key Points

To evaluate the CortiQ real-time functional mapping (RTFM) system in patients undergoing epilepsy surgery and compare its accuracy against electrical cortical stimulation mapping (ESM) and functional magnetic resonance imaging (fMRI).
Electrocorticographic activity was recorded and analyzed in real time in 3 male patients with intractable epilepsy using the CortiQ mapping system.
High gamma frequency band power (60–170 Hz) was evaluated during motor, sensory, and receptive language paradigms.
Sensitivity and specificity were evaluated using a quantitative 'next-neighbor' spatial approach benchmarked against ESM and fMRI.
Against ESM, RTFM demonstrated a sensitivity and specificity of 100.00% and 79.70% for hand motor, 100.00% and 73.87% for hand sensory, and -/87.00% specificity for receptive language (unidentified by ESM).
Against fMRI, RTFM demonstrated a sensitivity and specificity of 100.00% and 84.40% for hand motor, 66.70% and 85.35% for hand sensory, and 87.85% and 77.70% for receptive language.
RTFM correlated with fMRI language activation even when ESM yielded negative results, showing fewer procedural limitations and greater task flexibility than ESM.

Cite This Study

Kapeller et al. (2015) studied this question.

synapsesocial.com/papers/6a9db0629f8b6241c8680220 https://doi.org/10.1097/wnp.0000000000000131

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March 10, 2015Journal of Clinical Neurophysiology

CortiQ-based Real-Time Functional Mapping for Epilepsy Surgery

View Full Paper

Ask AI

Bookmark

Authors

CKChristoph KapellerGuger Technologies (Austria)MKMilena KorostenskajaUniversity of California, San Diego RPRobert PruecklJohannes Kepler University of Linz

Discussion

Member takes

Implication

Observational study reveals strong concordance between CortiQ real-time mapping, electrical stimulation, and fMRI in intractable epilepsy, highlighting a flexible tool for surgical guidance.

Key Points

To evaluate the CortiQ real-time functional mapping (RTFM) system in patients undergoing epilepsy surgery and compare its accuracy against electrical cortical stimulation mapping (ESM) and functional magnetic resonance imaging (fMRI).
Electrocorticographic activity was recorded and analyzed in real time in 3 male patients with intractable epilepsy using the CortiQ mapping system.
High gamma frequency band power (60–170 Hz) was evaluated during motor, sensory, and receptive language paradigms.
Sensitivity and specificity were evaluated using a quantitative 'next-neighbor' spatial approach benchmarked against ESM and fMRI.
Against ESM, RTFM demonstrated a sensitivity and specificity of 100.00% and 79.70% for hand motor, 100.00% and 73.87% for hand sensory, and -/87.00% specificity for receptive language (unidentified by ESM).
Against fMRI, RTFM demonstrated a sensitivity and specificity of 100.00% and 84.40% for hand motor, 66.70% and 85.35% for hand sensory, and 87.85% and 77.70% for receptive language.
RTFM correlated with fMRI language activation even when ESM yielded negative results, showing fewer procedural limitations and greater task flexibility than ESM.

Cite This Study

Kapeller et al. (2015) studied this question.

synapsesocial.com/papers/6a9db0629f8b6241c8680220 https://doi.org/10.1097/wnp.0000000000000131

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