Population
F-actin networks (in vitro model)
Comparison
Combination of alpha-actinin and filamin vs Alpha-actinin or filamin separately
Design
Preclinical
Authors
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Synergistic actin cross-linking may regulate cell migration mechanics; leaves open relevance to cardiovascular cytoskeletal dynamics.
Alpha-actinin and filamin synergistically enhance the stiffness of actin filament networks, suggesting non-redundant mechanical functions in generating cytoskeletal structures for cell migration.
Esue et al. (2009) studied this question.
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